Nicotiana rustica, known in South America as Mapacho, is a very potent variety of tobacco. Carl Linnaeus (Latinized as Carolus Linnaeus, also known after his ennoblement as, May 23 new style (13 May old style 1707 who laid the foundations for Tobacco is an Agricultural product recognized as an addictive drug processed from the fresh Leaves of plants in the genus Nicotiana. The high concentration of nicotine in its leaves makes it useful for creating organic pesticides. Nicotine is an Alkaloid found in the Nightshade family of plants ( Solanaceae) which constitutes approximately 0 A pesticide is a substance or mixture of substances used to kill a pest.
Rustica is also used for entheogenic purposes by South American shamans. An entheogen, in the strictest sense is a Psychoactive substance used in a religious or shamanic (or entheogenic) context South America is a Continent of the Americas, situated entirely in the Western Hemisphere and mostly in the Southern Hemisphere, with a Growing in the rainforest it contains up to twenty times more nicotine than common North American varieties such as N. tabacum. Most commonly, it is allowed to soak in water, and the water is then insufflated; it is also smoked in cigars and used as an enema. A cigar is a tightly rolled bundle of dried and fermented Tobacco which is ignited so that its smoke may be drawn into the smoker's mouth An enema (plural enemata or enemas) is the procedure of introducing liquids into the Rectum and colon via the Anus. It is also a common admixture of Ayahuasca in some parts of the rainforest. This entry focuses on the Ayahuasca brew for information on the vine of the same name see Banisteriopsis caapi Ayahuasca
Nicotiana rustica leaves have a nicotine content as high as 9%, whereas Nicotiana tabacum (common tobacco) leaves contain about 1 to 3%. Nicotiana tabacum, or cultivated Tobacco, is a perennial Herbaceous plant 
Bearing in mind all tobacco is very deadly and dangerous, Nicotiana rustica is the most potent and a very deadly species of tobacco due to its very high concentration of nicotine, a very powerful poison used as a pesticide. Death can result from skin contact when it is used as a pesticide as well as when it is smoked or injested.